Central questions for our research are
• How are external signals sensed by immune cells, how do lipids contribute to signal transfer across the cell membrane, and how do lipids modulate immune cell activation?
• What is the role of plasma membrane domains in immune cell activation?
• Can we modulate or control immune cell function by cell membrane composition?
and more general
• What are the physical driving forces for membrane domain formation?
• How is domain formation linked to plasma membrane asymmetry?
• How are plasma membrane asymmetry and biological membrane processes interlinked?
Applicants for doctoral positions:
Candidates should preferably hold a master degree in bio-/physics, theoretical/computational chem-istry, life sciences or similar and a strong interest in interdisciplinary projects and collaborations to medical/immunology groups.
The successful applicant has a keen interest and strong skills in methods from statistical and compu-tational physics, in particular atomistic and coarse-grained molecular dynamics simulations. The pro-ject involves close collaboration with immunology groups. The Postdoc will have the opportunity to participate in a research cluster studying the structure and function of immune domains.
Erlangen is a center for immunobiology with more than 70 groups focusing on immunological topics. In addition, since 2021, the University of Erlangen hosts a National High Performance Computing Center (hpc.fau.de) with a focus on atomistic simulations.